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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERBB4
All Species:
17.88
Human Site:
Y950
Identified Species:
39.33
UniProt:
Q15303
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15303
NP_001036064.1
1308
146808
Y950
P
I
C
T
I
D
V
Y
M
V
M
V
K
C
W
Chimpanzee
Pan troglodytes
XP_516067
1308
146816
Y950
P
I
C
T
I
D
V
Y
M
V
M
V
K
C
W
Rhesus Macaque
Macaca mulatta
XP_001113953
1342
148045
Y941
Q
I
C
T
I
D
V
Y
M
V
M
V
K
C
W
Dog
Lupus familis
XP_545629
1251
140621
M901
M
V
M
V
K
C
W
M
I
D
A
D
S
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61527
1292
145195
P940
L
E
K
G
E
R
L
P
Q
P
P
I
C
T
I
Rat
Rattus norvegicus
Q62956
1308
146940
Y950
P
I
C
T
I
D
V
Y
I
V
M
V
K
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508590
1260
141049
P910
G
K
P
Y
D
G
I
P
T
R
E
I
P
D
L
Chicken
Gallus gallus
P13387
703
77409
K353
G
I
G
I
G
E
L
K
G
I
L
S
I
N
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137223
1414
157718
Y939
P
I
C
T
I
D
V
Y
M
V
M
V
K
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04412
1426
159700
R1067
V
H
R
D
L
A
A
R
N
V
L
V
Q
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P24348
1323
150493
I961
M
H
D
D
G
L
K
I
V
T
I
Y
R
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
48.2
93.5
N.A.
96.1
96.5
N.A.
88
27.5
N.A.
66
N.A.
35.6
N.A.
20.7
N.A.
Protein Similarity:
100
99.9
63.4
94.8
N.A.
97.7
98.4
N.A.
90.6
36.3
N.A.
76
N.A.
50.9
N.A.
37.5
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
0
93.3
N.A.
0
6.6
N.A.
100
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
13.3
100
N.A.
13.3
33.3
N.A.
100
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
46
0
0
10
0
0
0
0
0
0
10
46
0
% C
% Asp:
0
0
10
19
10
46
0
0
0
10
0
10
0
10
0
% D
% Glu:
0
10
0
0
10
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
10
19
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
55
0
10
46
0
10
10
19
10
10
19
10
0
10
% I
% Lys:
0
10
10
0
10
0
10
10
0
0
0
0
46
0
0
% K
% Leu:
10
0
0
0
10
10
19
0
0
0
19
0
0
0
19
% L
% Met:
19
0
10
0
0
0
0
10
37
0
46
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
37
0
10
0
0
0
0
19
0
10
10
0
10
10
19
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
10
0
10
0
10
0
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
46
0
0
0
0
10
10
0
0
0
19
0
% T
% Val:
10
10
0
10
0
0
46
0
10
55
0
55
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
46
% W
% Tyr:
0
0
0
10
0
0
0
46
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _